Serial Brain MRI Findings in CNS Involvement of Familial Erythrophagocytic Lymphohistiocytosis: A Case Report

نویسندگان

  • Kyung Soo Cho
  • Jeong Soo Suh
  • Kyung Ha Ryu
  • Ki Sook Hong
  • Hak Jin Kim
چکیده

is a rare and fatal hereditary disorder of unknown cause with multisystem involvement. Involvement of the central nervous system (CNS) is reported in approximately 30% of cases. Leptomeningitis, gliosis, demyelination, and lymphocyte and histiocyte infiltration of the cerebrum and cerebellum are the characteristic neuropathologic findings. We describe the serial brain MRI findings and neurologic symptoms in a case of FEL, and review the literature.

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تاریخ انتشار 2002